Case-Based Learning in Biochemistry Through Inherited Metabolic Diseases

This book is intended for undergraduate biomedical and medical students, as well as residents and clinicians training in specialities related to biochemical genetics, including pathology, pediatrics, and medical genetics. Using real-world cases of inherited metabolic diseases (IMDs), it teaches fundamental concepts in biochemistry and genetics within a clinically relevant context. Each chapter presents a patient case resembling a clinical case record, followed by the associated biochemical findings, pathological features, and underlying metabolic mechanisms. To enhance student engagement and facilitate deeper learning, the book adopts a case-based learning (CBL) approach that integrates clinical practice with core biochemical and genetic principles. Through the analysis of patient cases, readers develop a practical understanding of disease pathophysiology while strengthening their clinical reasoning and problem-solving skills. The book also incorporates integrated educational methods and chapter-end self-assessment questions to reinforce key concepts and support knowledge retention.