Nanotechnology at Biointerfaces

This book Nanotechnology at Biointerfaces presents an engaging view of how nanoscale materials and molecular interfaces are reshaping surface chemistryand biophysics research and generating emerging technologies. Published in celebration of Professor Roger M. Leblanc’s, a true pioneer of the field,85th birthday and six decades of scientific achievement, the volume reflects a career that helped connect surface chemistry with living systems and gave a birth to the bionanotechnology. Its opening chapter follows Leblanc’s path from organized molecular films to modern bionanotechnology, setting the stage for a collection shaped by former students, collaborators, and international researchers. The chapters show how interfaces can become active platforms for diagnosis, imaging, molecular recognition, and therapeutic design. Langmuir films, peptide monolayers, membrane binding, and bioorthogonal chemistry appear alongside fluorescence nanoscopy, protein SAXS, atomic force microscopy, and nano-oscillator sensing. These approaches may reveal molecular events that remain hidden in conventional bulk measurements. Readers will find concrete examples involving DNA and chromatin labels, transmembrane proteins in the visual cycle, and label-free detection of small molecules or individual proteins. Carbon nanomaterials form a major theme throughout the book and are a major theme in Roger Leblans research opus. Red-emissive carbon dots, hybrid architectures, photothermal treatment, and immunotherapy illustrate their expanding biomedical promise. Further chapters address blood testing, environmental remediation, mechanical lysis of difficult samples, and PROTAC development. The final contribution considers how deep-tech discoveries can move from invention toward scalable use. This volume offers researchers and graduate students a timely guide to interfacial nanotechnology where chemistry meets biology at the interface.